Calosent: Advanced Calcium and Immunity Booster Effervescent Tablet in Pakistan
Calosent effervescent tablets pair calcium with vitamin D3, C and B6 to support bone health and immunity. What is on the label and how it compares.
Pakistan’s National Nutrition Survey 2018 found anaemia in 42.7 percent of women of reproductive age, with iron deficiency anaemia in 18.4 percent of them (NNS 2018 analysis, published in Nutrients). Bone health is just as worrying. A review in Annals of Medicine and Surgery puts osteoporosis at 20 to 49.3 percent of postmenopausal Pakistani women and 5.6 to 17.8 percent of premenopausal women, and notes that DXA scanners exist only in the larger cities, so most cases are never measured at all. Vitamin D deficiency sits underneath both problems: a study of 26,750 people in Karachi found 56 percent deficient and another 20 percent insufficient.
The everyday Pakistani diet does not help. It is heavy on roti, rice and chai, and light on dairy and leafy greens. MedlinePlus puts the adult requirement at 1,000 mg of calcium a day, rising to 1,200 mg for women over 50, and a day without milk, dahi or cheese in it rarely gets close.
Pharmacy shelves are not much comfort either: imported bone formulas, chalky calcium carbonate tablets that sit heavily in the stomach, and effervescents priced like a treat rather than a habit. Calosent by NB Sons is the local answer to that. At Rs 350 it uses a dual-calcium formula, Calcium Lactate Gluconate 1000 mg with Calcium Carbonate 300 mg, and adds Vitamin D3 400 IU, Vitamin C 500 mg and Vitamin B6 10 mg in a tablet that dissolves in a glass of water.
That combination is what makes it worth a look. Plenty of calcium products in Pakistan give you calcium and stop there. Calosent covers the calcium, the vitamin D3 that lets your gut absorb it, and the vitamin C and B6 that matter for the other gap most Pakistani households have, which is iron.
Shop the picks in this guide (5)
- Calosent Effervescent Calcium, Rs 350, the fizzy daily calcium with D3, C and B6 this guide is about
- Calin-G Calcium + Vitamin D3, Rs 420, the plain swallowed tablet if you would rather not pay for the fizz
- Vit KD, D3 10,000 IU with K2, Rs 870, for a diagnosed vitamin D deficiency, at the dose your doctor sets
- Calco Fit Magnesium Glycinate 500 mg, Rs 1,290, the evening partner for muscles and sleep
- Strong Bones & Joint Health Combo, Rs 3,586, five NB Sons bone and joint products in one pack
Table of Contents
- What Is Calosent?
- Full Composition Breakdown
- Why the Effervescent Format Can Help
- Bone Health: Why Pakistan Needs Better Calcium
- Immunity Support: The Vitamin C and D3 Advantage
- Iron Absorption and Anaemia Risk
- Who Should Take Calosent?
- How to Use Calosent for Best Results
- Calosent vs CAC-1000 Plus and Other Calcium Supplements
- Frequently Asked Questions
- Where to Buy Calosent in Pakistan
What Is Calosent?
Calosent is an effervescent calcium and immunity supplement from NB Sons, the Pakistani company behind Calin-G, Vit KD and ArtiBro. Each tablet drops into a glass of water and carries a full mineral and vitamin load rather than calcium alone.
The effervescent format is doing more than making the dose pleasant to drink. By the time you drink it, the tablet has already broken up in the glass, so the calcium arrives dissolved instead of as a compressed disc your stomach has to take apart. Anyone who has swallowed a chalky calcium tablet and felt it sitting there afterwards will understand the appeal.
What separates Calosent from a plain calcium effervescent is the rest of the label. It carries the Vitamin D3 your gut needs in order to absorb calcium at all, the Vitamin C that supports immune defence and collagen, and Vitamin B6. All of it comes in one daily tablet at a price close to what plain calcium costs.
Full Composition Breakdown
| Ingredient | Amount | Function |
|---|---|---|
| Calcium Lactate Gluconate (USP) | 1000 mg | The main calcium salt, highly soluble, which is what makes an effervescent tablet possible |
| Calcium Carbonate (USP) | 300 mg | A second calcium salt, the most concentrated common form by weight, and mildly antacid |
| Vitamin D3 (USP) | 400 IU | Your body needs vitamin D to use calcium, which is why calcium products are usually paired with it |
| Vitamin C (USP) | 500 mg | Immune support, collagen formation, antioxidant protection, and better absorption of iron from food |
| Vitamin B6 (USP) | 10 mg | Normal metabolism, nervous system function and red blood cell formation |
Composition is as printed on the NB Sons pack. The dual-calcium approach is deliberate. Calcium lactate gluconate is one of the most soluble calcium salts available, so it dissolves fully in water, which is exactly what an effervescent tablet needs. Calcium carbonate carries the highest share of elemental calcium per milligram of the common forms, so it adds calcium without adding much bulk to the tablet. Between them the tablet delivers roughly the same calcium load as Pakistan’s best-known effervescent, which we come back to below.
Every active on the label is listed at USP grade, the United States Pharmacopeia standard for identity, strength and purity. It is a specification for the raw material, not a claim about what the finished product does.
Why the Effervescent Format Can Help
Effervescent versus solid calcium is mostly a question of what you will actually take every day, with one real difference in the glass. Here is what happens with a standard calcium carbonate tablet:
- The tablet reaches your stomach intact
- Stomach acid has to break it down before any calcium is free to absorb
- If your stomach acid is low, which is more common with age and on long-term antacids, that takes longer
- This is why calcium carbonate tablets are meant to be taken with food, when acid production is highest
Now here is what happens with Calosent:
- The tablet dissolves fully in water before you drink it
- The calcium is already in solution when it reaches your stomach
- There is no compressed tablet left for your stomach to break apart
- The carbonate share still does better with a meal, so take it with food
Nobody should oversell this. The evidence on effervescent calcium absorbing better than an ordinary tablet is thin, and a calcium supplement you take reliably will always beat a better one sitting in a drawer. What the format definitely does is remove the swallowing problem, which matters for older people and anyone who gags on large tablets, and it means you drink a full glass of water with every dose.
Bone Health: Why Pakistan Needs Better Calcium
The numbers are sobering. That review in Annals of Medicine and Surgery puts osteoporosis at 20 to 49.3 percent of postmenopausal women in Pakistan and 5.6 to 17.8 percent of premenopausal women, with osteopenia far more common still. Men are not exempt, and because DXA scanners are scarce outside the big cities, plenty of thin bones here are never diagnosed until something breaks.
Three factors drive the problem:
1. Dietary Calcium Deficit
Adults need about 1,000 mg of calcium a day, and 1,200 mg for women over 50, according to MedlinePlus. Diets built on roti, rice and daal with limited dairy do not get there on their own, even with the occasional serving of paneer or yoghurt. The NHS sets a lower target, 700 mg a day for adults, and still expects most of it to come from food rather than a tablet, which is a fair reminder that supplements are a top-up and not the plan.
2. Widespread Vitamin D Deficiency
Pakistan gets plenty of sun and very little vitamin D from it. Indoor work, covered clothing and limited outdoor time do the damage: in that Karachi study of 26,750 people, 56 percent were deficient and 20 percent insufficient, with teenagers worst affected at 71 percent. Vitamin D is what lets your body use the calcium you swallow, which is why MedlinePlus advises picking a calcium supplement that contains it. Calosent includes 400 IU of Vitamin D3 for that reason. If you have a diagnosed deficiency, 400 IU is a maintenance amount rather than a correction, and a prescribed high-dose product such as Vit KD is the doctor’s tool for that job.
3. Lifestyle Factors
Sitting all day, smoking and a lack of weight-bearing exercise all work against bone density. Urban Pakistanis, the same group most likely to buy supplements, tend to collect the largest number of these risks at once.
Calosent covers the calcium and the vitamin D parts of the problem in one glass. It does not cover the walking, and no tablet does.
Immunity Support: The Vitamin C and D3 Advantage
Most people file calcium supplements under bones and nothing else. Calosent is built wider than that, and in Pakistan the extra vitamins are not padding.
Each tablet carries 500 mg of Vitamin C. For scale, the NHS puts the adult requirement at 40 mg a day and says intakes below 1,000 mg a day from supplements are unlikely to cause harm, so 500 mg is a generous daily amount that stays inside that range. The NHS credits vitamin C with:
- Protecting cells and helping keep them healthy
- Maintaining skin, blood vessels, bones and cartilage, the collagen-dependent tissues
- Wound healing, which is why it turns up in recovery advice after surgery or injury
Add Vitamin D3 400 IU and the tablet supports normal immune function from a second direction. Given how common low vitamin D is here, that 400 IU is filling a real gap for a lot of people rather than topping up an already adequate level. Note the honest limit: supporting normal immune function is not the same as preventing infections, and no supplement stops you catching flu.
For families going through flu season, Lahore’s smog months and the general germ load of a crowded city, one daily tablet that covers bone and immune support at the same time is a reasonable piece of housekeeping.
Iron Absorption and Anaemia Risk
Anaemia is one of Pakistan’s most common nutritional problems. The National Nutrition Survey 2018 found 42.7 percent of women of reproductive age anaemic and 53.7 percent of children under five, with iron deficiency behind a large share of it.
Calosent helps here indirectly, through the vitamin C. Research in The Journal of Nutrition describes how ascorbic acid enhances non-haem iron uptake by reducing dietary ferric iron to the ferrous form in the gut. Non-haem iron is the kind in spinach, daal and chana, the staples of most Pakistani plates, and it is poorly absorbed on its own. The same work found that tea polyphenols block iron absorption in a dose-dependent way, and that vitamin C can offset that inhibition. In a country that runs on chai with meals, that pairing matters.
Vitamin B6 (10 mg) supports normal red blood cell formation, which is a supporting role in the same story rather than a replacement for iron.
One caution that belongs here rather than in the small print: calcium itself competes with iron. If a doctor has put you on an iron tablet, take it at the other end of the day from your calcium, and do not treat Calosent as anaemia treatment. It is not one.
Who Should Take Calosent?
| Group | Why Calosent Helps | Key Benefits |
|---|---|---|
| Women over 35 | Bone loss starts before menopause and runs quietly | Calcium with D3 for bone support, vitamin C for skin and immunity |
| Post-menopausal women | The group with the highest measured osteoporosis rates in Pakistan | Daily calcium and D3 at the 1,200 mg target age |
| Men over 50 | Bone loss happens in men too and is rarely screened for here | Everyday bone maintenance in a format people keep up |
| Pregnant and nursing women* | Calcium and vitamin D matter for mother and baby | Supports maternal bone health, on your doctor’s advice |
| Teenagers (growth phase) | Ages 9 to 18 have the highest calcium requirement of any group, 1,300 mg a day | Calcium during the bone-building years |
| Women at risk of anaemia | Vitamin C improves iron absorption from food; B6 supports red blood cell formation | Helps the iron in your meals go further |
| Frequent tea drinkers | Tea polyphenols reduce iron absorption from food | Vitamin C offsets some of that effect |
| People who struggle with tablets | Low stomach acid and swallowing difficulty both make solid calcium harder work | Dissolves in water, nothing to swallow |
*Pregnant and nursing women should consult their healthcare provider before starting any supplement.
How to Use Calosent for Best Results
Preparation
Drop one Calosent effervescent tablet into a glass of water, about 200 ml. Let it dissolve fully, which usually takes a minute or two. Drink it straight away while it is still fizzing.
Best Time to Take
- With a meal: food helps the calcium carbonate share absorb, so take it with or just after food, once daily or as your doctor directs
- Morning or afternoon: most people find it easiest to attach to breakfast, which is what makes it stick
- Away from chai: if you drink a lot of tea, leave an hour between your cup and your tablet, since tea polyphenols work against iron absorption from the same meals
Combinations That Make Sense
Calosent pairs well with other NB Sons supplements:
- Calco Fit (magnesium glycinate 500 mg): magnesium works alongside calcium in bone and muscle, and the glycinate form is gentle on the stomach. Take Calco Fit in the evening, where it also supports sleep and relaxed muscles, and Calosent in the morning
- Vit KD (vitamin D3 10,000 IU with K2 as MK-7): for people with a diagnosed vitamin D deficiency who need more than the 400 IU in Calosent. That strength is a doctor’s call, not a daily default
- ArtiBro (glucosamine, chondroitin, hyaluronic acid and curcuma): for joint comfort when you also want calcium for the bone underneath. Calosent, Calco Fit, Vit KD, ArtiBro and Calin-G sit together in the Strong Bones & Joint Health Combo if you would rather buy the routine in one go
Safety Notes
- Do not exceed the recommended daily dose. The NHS notes that calcium intakes above 1,500 mg a day can cause stomach pain and diarrhoea
- Space calcium at least 2 hours from thyroid medicines, antibiotics (tetracycline, fluoroquinolones) and bisphosphonates
- If you take an iron supplement, take it at a different time of day, since calcium reduces iron absorption
- Anyone with kidney disease, a history of kidney stones or a heart condition should clear a calcium supplement with their doctor first
- Store in a cool, dry place away from moisture, since effervescent tablets are sensitive to humidity
Calosent vs CAC-1000 Plus and Other Calcium Supplements
CAC-1000 Plus by Haleon (formerly GSK) has led Pakistan’s calcium market for years, to the point where people say the brand name when they mean calcium. Our full CAC-1000 Plus guide goes through its label, its checked pharmacy prices and who genuinely needs it. Here is how the three compare:
| Feature | Calosent (NB Sons) | CAC-1000 Plus (Haleon) | Nutrifactor Bonex-D |
|---|---|---|---|
| Format | Effervescent tablet | Effervescent tablet | Swallowed tablet |
| Calcium salts | Lactate gluconate 1000 mg + carbonate 300 mg | Lactate gluconate 1000 mg + carbonate 327 mg | Carbonate 600 mg |
| Vitamin D3 | 400 IU | 400 IU | 400 IU |
| Vitamin C | 500 mg | 500 mg | Not included |
| Vitamin B6 | 10 mg | 10 mg | Not included |
| Pack price | Rs 350 | About Rs 270 to Rs 303 for 10 tablets, about Rs 656 for 20 | Rs 690 for 30 tablets |
Only the Calosent price is live on this page. The CAC-1000 Plus figures were checked in August 2026 at Pakistani pharmacies that deliver nationwide, and the Bonex-D figure is the price on Nutrifactor’s own site in September 2026. Pharmacy prices move, so treat both as a guide rather than a quote.
The honest headline is that Calosent and CAC-1000 Plus are close cousins. Same effervescent format, the same two calcium salts at almost the same strengths, the same 400 IU of D3, the same 500 mg of vitamin C and the same 10 mg of B6. Anyone telling you one of them is missing a vitamin the other has is reading an out-of-date label. The choice between them comes down to brand preference, taste and what each pack works out to per tablet, so divide the pack price by the tablet count printed on it before you decide.
Nutrifactor Bonex-D takes a different route. It is an ordinary swallowed tablet with calcium carbonate 600 mg and vitamin D3 400 IU, no vitamin C and no B6, in packs of 30, 60 and 120. If all you want is calcium with D3 and you have no trouble swallowing tablets, that is a perfectly sensible thing to want, and our own Calin-G does the same job with calcium carbonate 500 mg and vitamin D3 400 IU at Rs 420.
Where to Buy Calosent in Pakistan
Order Calosent from Yellow Pink for delivery to Karachi, Lahore, Islamabad, Rawalpindi, Peshawar, Faisalabad, Multan and everywhere else in the country. Cash on delivery is available across Pakistan, and delivery is free on orders over Rs 5,000 in Punjab.
At Rs 350 a pack, Calosent is one of the more affordable complete calcium supplements you can buy here: pharmaceutical-grade calcium with vitamin D3, vitamin C and vitamin B6 on one label, in a format people actually keep up with. In a country where low calcium, low vitamin D and anaemia all turn up in the same household, a single tablet that touches all three is a sensible thing to keep on the kitchen shelf.
This article was written and medically reviewed to our medical review board standards and is for general guidance, not personal medical advice. Always speak to a doctor or pharmacist about your own situation.
If you want the fizzy glass and a complete label, start with Calosent. If you would rather swallow a plain tablet, Calin-G covers the same calcium and D3 job, and the rest of the range sits on our bone and joint page. Cash on delivery across Pakistan, free delivery over Rs 5,000 in Punjab.
Frequently asked questions
What is Calosent Effervescent and how does it work?
Calosent is a dissolvable supplement that combines calcium lactate gluconate 1000 mg, calcium carbonate 300 mg, vitamin D3 400 IU, vitamin C 500 mg and vitamin B6 10 mg. You drop the tablet in a glass of water, let it dissolve fully and drink it. Because it dissolves in the glass, your stomach does not have to break down a compressed tablet first, which suits people who find calcium tablets heavy going.
What benefits can I expect from taking Calosent daily?
It supports bone health through calcium and vitamin D3, supports normal immune function through vitamin C and D3, helps your body absorb more iron from the food you eat, and supports normal red blood cell formation and metabolism through vitamin B6. It is a daily top-up alongside a reasonable diet, and it works quietly rather than producing an effect you feel in a week.
How should Calosent be used and are there any safety tips?
Drop one effervescent tablet into a glass of water (200 ml), let it dissolve fully and drink it straight away, with or just after a meal. Do not take more than one tablet a day unless your doctor advises it. Keep it at least 2 hours away from antibiotics and thyroid medicines, take any iron tablet at the other end of the day, and store the tube somewhere cool and dry.
Is Calosent better than CAC-1000 Plus?
Not in composition terms. The two labels are almost identical: the same calcium salts at almost the same strengths, and the same vitamin D3 400 IU, vitamin C 500 mg and vitamin B6 10 mg. The real comparison is what each pack costs per tablet, and which one you will actually keep drinking every day.
Can pregnant women take Calosent?
Calcium and vitamin D matter in pregnancy, and doctors in Pakistan commonly prescribe a calcium supplement. Even so, check with your own healthcare provider before starting Calosent, so it fits with your prenatal vitamins, your iron tablet and anything else you are taking.
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